18β-Glycyrrhetinic-acid-mediated unfolded protein response induces autophagy and apoptosis in hepatocellular carcinoma

18β-Glycyrrhetinic acid (GA) is the active ingredient of the traditional Chinese medicine, Glycyrrhrzae Radix et Rhizoma. Here, we explored the effects of GA on hepatocellular carcinoma (HCC) in vitro and in vivo and the underlying molecular mechanisms. We confirmed that GA suppressed proliferation...

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Detalles Bibliográficos
Autores principales: Chen, Jin, Zhang, Zhao-qi, Song, Jia, Liu, Qiu-meng, Wang, Chao, Huang, Zhao, Chu, Liang, Liang, Hui-fang, Zhang, Bi-xiang, Chen, Xiao-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008326/
https://www.ncbi.nlm.nih.gov/pubmed/29921924
http://dx.doi.org/10.1038/s41598-018-27142-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008326/
https://www.ncbi.nlm.nih.gov/pubmed/29921924
http://dx.doi.org/10.1038/s41598-018-27142-5

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