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A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection

Whole blood transcriptional signatures distinguishing active tuberculosis patients from asymptomatic latently infected individuals exist. Consensus has not been achieved regarding the optimal reduced gene sets as diagnostic biomarkers that also achieve discrimination from other diseases. Here we sho...

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Detalles Bibliográficos
Autores principales: Singhania, Akul, Verma, Raman, Graham, Christine M., Lee, Jo, Tran, Trang, Richardson, Matthew, Lecine, Patrick, Leissner, Philippe, Berry, Matthew P. R., Wilkinson, Robert J., Kaiser, Karine, Rodrigue, Marc, Woltmann, Gerrit, Haldar, Pranabashis, O’Garra, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008327/
https://www.ncbi.nlm.nih.gov/pubmed/29921861
http://dx.doi.org/10.1038/s41467-018-04579-w