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Protective effects of systemic dermatan sulfate treatment in a preclinical model of radiation-induced oral mucositis

PURPOSE: Oral mucositis is a frequent, dose-limiting side effect of radio(chemo)therapy of head-and-neck malignancies. The epithelial radiation response is based on multiple tissue changes, which could offer targets for a biologically tailored treatment. The potential of dermatan sulfate (DS) to mod...

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Detalles Bibliográficos
Autores principales: Gruber, Sylvia, Frings, Katharina, Kuess, Peter, Dörr, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008363/
https://www.ncbi.nlm.nih.gov/pubmed/29497792
http://dx.doi.org/10.1007/s00066-018-1280-8