The Thrombin Receptor Restricts Subventricular Zone Neural Stem Cell Expansion and Differentiation

Thrombin is frequently increased in the CNS after injury yet little is known regarding its effects on neural stem cells. Here we show that the subventricular zone (SVZ) of adult mice lacking the high affinity receptor for thrombin, proteinase activated receptor 1 (PAR1), show increased numbers of So...

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Detalles Bibliográficos
Autores principales: Choi, Chan-Il, Yoon, Hyesook, Drucker, Kristen L., Langley, Monica R., Kleppe, Laurel, Scarisbrick, Isobel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008392/
https://www.ncbi.nlm.nih.gov/pubmed/29921916
http://dx.doi.org/10.1038/s41598-018-27613-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008392/
https://www.ncbi.nlm.nih.gov/pubmed/29921916
http://dx.doi.org/10.1038/s41598-018-27613-9

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