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Influenza viral vectors expressing two kinds of HA proteins for bivalent vaccines against clade 2.3.4.4 and clade 2.3.2.1 H5 HPAIVs

The H5 highly pathogenic avian influenza viruses (HPAIVs) in China pose a serious challenge to public health and the poultry industry. In this study, we constructed a replication-competent recombinant influenza A virus of clade 2.3.4.4 Н5N1 expressing the clade 2.3.2.1 H5 HA1 protein from a tricistr...

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Detalles Bibliográficos
Autores principales: Hou, Guangyu, Li, Jinping, Wang, Yan, Wang, Suchun, Peng, Cheng, Yu, Xiaohui, Jin, Jihui, Jiang, Wenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008415/
https://www.ncbi.nlm.nih.gov/pubmed/29921911
http://dx.doi.org/10.1038/s41598-018-27722-5