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HEPATOKIN1 is a biochemistry-based model of liver metabolism for applications in medicine and pharmacology

The epidemic increase of non-alcoholic fatty liver diseases (NAFLD) requires a deeper understanding of the regulatory circuits controlling the response of liver metabolism to nutritional challenges, medical drugs, and genetic enzyme variants. As in vivo studies of human liver metabolism are encumber...

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Detalles Bibliográficos
Autores principales: Berndt, Nikolaus, Bulik, Sascha, Wallach, Iwona, Wünsch, Tilo, König, Matthias, Stockmann, Martin, Meierhofer, David, Holzhütter, Hermann-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008457/
https://www.ncbi.nlm.nih.gov/pubmed/29921957
http://dx.doi.org/10.1038/s41467-018-04720-9