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HEPATOKIN1 is a biochemistry-based model of liver metabolism for applications in medicine and pharmacology
The epidemic increase of non-alcoholic fatty liver diseases (NAFLD) requires a deeper understanding of the regulatory circuits controlling the response of liver metabolism to nutritional challenges, medical drugs, and genetic enzyme variants. As in vivo studies of human liver metabolism are encumber...
Autores principales: | Berndt, Nikolaus, Bulik, Sascha, Wallach, Iwona, Wünsch, Tilo, König, Matthias, Stockmann, Martin, Meierhofer, David, Holzhütter, Hermann-Georg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008457/ https://www.ncbi.nlm.nih.gov/pubmed/29921957 http://dx.doi.org/10.1038/s41467-018-04720-9 |
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