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Altered Functions and Interactions of Glaucoma-Associated Mutants of Optineurin
Optineurin (OPTN) is an adaptor protein that is involved in mediating a variety of cellular processes such as signaling, vesicle trafficking, and autophagy. Certain mutations in OPTN (gene OPTN) are associated with primary open angle glaucoma, a leading cause of irreversible blindness, and amyotroph...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008547/ https://www.ncbi.nlm.nih.gov/pubmed/29951055 http://dx.doi.org/10.3389/fimmu.2018.01287 |