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Storage-Induced Platelet Apoptosis Is a Potential Risk Factor for Alloimmunization Upon Platelet Transfusion

Platelet transfusion can elicit alloimmune responses leading to alloantibody formation against donor-specific polymorphic residues, ultimately resulting in platelet transfusion refractoriness. Universal leukoreduction significantly reduced the frequency of alloimmunization after platelet transfusion...

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Detalles Bibliográficos
Autores principales: Saris, Anno, Peyron, Ivan, van der Meer, Pieter F., Stuge, Tor B., Zwaginga, Jaap Jan, van Ham, S. Marieke, ten Brinke, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008548/
https://www.ncbi.nlm.nih.gov/pubmed/29951051
http://dx.doi.org/10.3389/fimmu.2018.01251