6′-Hydroxy Justicidin B Triggers a Critical Imbalance in Ca(2+) Homeostasis and Mitochondrion-Dependent Cell Death in Human Leukemia K562 Cells

Justicia procumbens (J. procumbens) is a traditional Chinese herbal medicine which was used for the treatment of fever, pain, and cancer. A compound 6′-hydroxy justicidin B (HJB) isolated from J. procumbens exhibits promising biological properties. However, the mechanism of action and the in vivo be...

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Detalles Bibliográficos
Autores principales: Luo, Jiaoyang, Qin, Jiaan, Fu, Yanwei, Zhang, Shanshan, Zhang, Xingguo, Yang, Meihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008565/
https://www.ncbi.nlm.nih.gov/pubmed/29950991
http://dx.doi.org/10.3389/fphar.2018.00601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008565/
https://www.ncbi.nlm.nih.gov/pubmed/29950991
http://dx.doi.org/10.3389/fphar.2018.00601

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