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6′-Hydroxy Justicidin B Triggers a Critical Imbalance in Ca(2+) Homeostasis and Mitochondrion-Dependent Cell Death in Human Leukemia K562 Cells
Justicia procumbens (J. procumbens) is a traditional Chinese herbal medicine which was used for the treatment of fever, pain, and cancer. A compound 6′-hydroxy justicidin B (HJB) isolated from J. procumbens exhibits promising biological properties. However, the mechanism of action and the in vivo be...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008565/ https://www.ncbi.nlm.nih.gov/pubmed/29950991 http://dx.doi.org/10.3389/fphar.2018.00601 |