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Modulatory Effects of a Novel Cyclized Peptide in Reducing the Expression of Markers Linked to Alzheimer's Disease

Despite many studies attempt to identify the primary mechanisms underlying neurodegeneration in Alzheimer's disease (AD), the key events still remain elusive. We have previously shown that a peptide cleaved from the acetylcholinesterase (AChE) C-terminus (T14) can play a pivotal role as a signa...

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Detalles Bibliográficos
Autores principales: Brai, Emanuele, Simon, Florian, Cogoni, Antonella, Greenfield, Susan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008575/
https://www.ncbi.nlm.nih.gov/pubmed/29950969
http://dx.doi.org/10.3389/fnins.2018.00362