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Phase I and II trial on infusional 5-fluorouracil and gefitinib in combination with preoperative radiotherapy in rectal cancer: 10-years median follow-up

PURPOSE: The aim of this study is to evaluate the long term survival of the addition of gefitinib to chemoradiotherapy (CRT) in locally advanced rectal cancer (LARC). METHODS AND MATERIALS: This previously published multicentre, open-label, phase I-II study, enrolled patients (pts) with LARC to rece...

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Detalles Bibliográficos
Autores principales: Gambacorta, Maria Antonietta, De Paoli, Antonino, Lupattelli, Marco, Chiloiro, Giuditta, Solazzo, Angela Pia, Barbaro, Brunella, Alfieri, Sergio, Vecchio, Fabio Maria, Lenkowicz, Jacopo, Navarria, Francesco, Palazzari, Elisa, Bertola, Giulio, Frattegiani, Alessandro, Minsky, Bruce, Valentini, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008630/
https://www.ncbi.nlm.nih.gov/pubmed/29928702
http://dx.doi.org/10.1016/j.ctro.2018.02.003