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Identification of the active portion of the CCL3 derivative reported to induce antitumor abscopal effect

BACKGROUND AND PURPOSE: Intravenous administration of a single amino acid-substituted chemokine CCL3 derivative named eMIP elicits the abscopal effect (an effect distal to the target), after local irradiation at a tumor-bearing site. To distinguish the active portion of eMIP, we tested the antitumor...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Tomoko, Shiraishi, Kenshiro, Nakagawa, Keiichi, Kim, Jae-Ryong, Kanegasaki, Shiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008634/
https://www.ncbi.nlm.nih.gov/pubmed/29928700
http://dx.doi.org/10.1016/j.ctro.2018.02.004