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Impaired Mitophagy of Nucleated Erythroid Cells Leads to Anemia in Patients with Myelodysplastic Syndromes

Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal stem cell disorders characterized by cytopenia and dysplasia. Anemia is the most common symptom in patients with MDS. Mitophagy and mitochondrial dysfunction might be involved in the development of MDS. In this study, we investigate...

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Detalles Bibliográficos
Autores principales: Jiang, Huijuan, Yang, Liyan, Guo, Lifang, Cui, Ningbo, Zhang, Gaochao, Liu, Chunyan, Xing, Limin, Shao, Zonghong, Wang, Huaquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008680/
https://www.ncbi.nlm.nih.gov/pubmed/29967662
http://dx.doi.org/10.1155/2018/6328051