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Evoked and Ongoing Pain-Like Behaviours in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy

Paclitaxel-induced neuropathic pain is a major dose-limiting side effect of paclitaxel therapy. This study characterises a variety of rat behavioural responses induced by intermittent administration of clinically formulated paclitaxel. 2 mg/kg paclitaxel or equivalent vehicle was administered intrap...

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Detalles Bibliográficos
Autores principales: Griffiths, Lisa A., Duggett, Natalie A., Pitcher, Ann L., Flatters, Sarah J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008701/
https://www.ncbi.nlm.nih.gov/pubmed/29973969
http://dx.doi.org/10.1155/2018/8217613