Cargando…

Atomistic picture of conformational exchange in a T4 lysozyme cavity mutant: an experiment-guided molecular dynamics study

Despite the importance of dynamics to protein function there is little information about the states that are formed as the protein explores its conformational landscape or about the mechanism by which transitions between the different states occur. Here we used a combined NMR spin relaxation and unb...

Descripción completa

Detalles Bibliográficos
Autores principales: Vallurupalli, Pramodh, Chakrabarti, Nilmadhab, Pomès, Régis, Kay, Lewis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008728/
https://www.ncbi.nlm.nih.gov/pubmed/30008994
http://dx.doi.org/10.1039/c5sc03886c