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Atomistic picture of conformational exchange in a T4 lysozyme cavity mutant: an experiment-guided molecular dynamics study
Despite the importance of dynamics to protein function there is little information about the states that are formed as the protein explores its conformational landscape or about the mechanism by which transitions between the different states occur. Here we used a combined NMR spin relaxation and unb...
Autores principales: | Vallurupalli, Pramodh, Chakrabarti, Nilmadhab, Pomès, Régis, Kay, Lewis E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008728/ https://www.ncbi.nlm.nih.gov/pubmed/30008994 http://dx.doi.org/10.1039/c5sc03886c |
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