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A method for transplantation of human HSCs into zebrafish, to replace humanised murine transplantation models

Haematopoietic stem cell (HSC) transplantation is a critical therapy for haematopoietic malignancies and immune disorders. Incomplete or delayed engraftment of HSCs in the host results in increased risk of infection and morbidity. The mechanisms of HSC engraftment are poorly understood and understan...

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Detalles Bibliográficos
Autores principales: Hamilton, Noémie, Sabroe, Ian, Renshaw, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008850/
https://www.ncbi.nlm.nih.gov/pubmed/29946444
http://dx.doi.org/10.12688/f1000research.14507.2