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TGF-β signaling promotes tumor vasculature by enhancing the pericyte-endothelium association

BACKGROUND: The breast cancer microenvironment promotes tumor vascularization through the complex interactions involving tumor-associated fibroblasts (TAFs). Emerging data indicate that TAFs increase production and signaling by TGF-β cytokines, while the role of TGF-β signaling in the regulation of...

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Detalles Bibliográficos
Autores principales: Zonneville, Justin, Safina, Alfiya, Truskinovsky, Alexander M., Arteaga, Carlos L., Bakin, Andrei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008941/
https://www.ncbi.nlm.nih.gov/pubmed/29921235
http://dx.doi.org/10.1186/s12885-018-4587-z