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TGF-β signaling promotes tumor vasculature by enhancing the pericyte-endothelium association
BACKGROUND: The breast cancer microenvironment promotes tumor vascularization through the complex interactions involving tumor-associated fibroblasts (TAFs). Emerging data indicate that TAFs increase production and signaling by TGF-β cytokines, while the role of TGF-β signaling in the regulation of...
Autores principales: | Zonneville, Justin, Safina, Alfiya, Truskinovsky, Alexander M., Arteaga, Carlos L., Bakin, Andrei V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008941/ https://www.ncbi.nlm.nih.gov/pubmed/29921235 http://dx.doi.org/10.1186/s12885-018-4587-z |
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