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NICD-mediated notch transduction regulates the different fate of chicken primordial germ cells and spermatogonial stem cells

BACKGROUND: Notch signaling is mainly regulated by Notch1 during development of chicken germ stem cells; however, the molecular mechanisms that contribute to generation of these germ stem cells have not been thoroughly investigated. RESULTS: In our studies, Overexpression of the Notch1 NICD promoted...

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Detalles Bibliográficos
Autores principales: Zuo, Qisheng, Zhang, Chen, Jin, Kai, Jing, Jin, Sun, Changhua, Ahmed, Mahmoud F., Song, Jiuzhou, Zhang, Yani, Chen, Guohong, Li, Bichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009047/
https://www.ncbi.nlm.nih.gov/pubmed/29951200
http://dx.doi.org/10.1186/s13578-018-0238-y