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SNAI2 upregulation is associated with an aggressive phenotype in fulvestrant-resistant breast cancer cells and is an indicator of poor response to endocrine therapy in estrogen receptor-positive metastatic breast cancer

BACKGROUND: Endocrine resistance in estrogen receptor-positive (ER+) breast cancer is a major clinical problem and is associated with accelerated cancer cell growth, increased motility and acquisition of mesenchymal characteristics. However, the specific molecules and pathways involved in these alte...

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Detalles Bibliográficos
Autores principales: Alves, Carla L., Elias, Daniel, Lyng, Maria B., Bak, Martin, Ditzel, Henrik J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009053/
https://www.ncbi.nlm.nih.gov/pubmed/29921289
http://dx.doi.org/10.1186/s13058-018-0988-9