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Synthesis of pyrazolopyrimidinones using a “one-pot” approach under microwave irradiation

A simple one-pot method for the microwave-assisted synthesis of substituted pyrazolo[1,5-a]pyrimidinones, a core scaffold in many bioactive and pharmaceutically relevant compounds, has been established. A variety of substituents was tolerated at the 2 and 5 positions, including functionalized aryls,...

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Detalles Bibliográficos
Autores principales: Kelada, Mark, Walsh, John M D, Devine, Robert W, McArdle, Patrick, Stephens, John C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009099/
https://www.ncbi.nlm.nih.gov/pubmed/29977390
http://dx.doi.org/10.3762/bjoc.14.104