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Oligonucleotide analogues with cationic backbone linkages

Their unique ability to selectively bind specific nucleic acid sequences makes oligonucleotides promising bioactive agents. However, modifications of the nucleic acid structure are an essential prerequisite for their application in vivo or even in cellulo. The oligoanionic backbone structure of olig...

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Detalles Bibliográficos
Autores principales: Meng, Melissa, Ducho, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009206/
https://www.ncbi.nlm.nih.gov/pubmed/29977397
http://dx.doi.org/10.3762/bjoc.14.111