Cargando…
Oligonucleotide analogues with cationic backbone linkages
Their unique ability to selectively bind specific nucleic acid sequences makes oligonucleotides promising bioactive agents. However, modifications of the nucleic acid structure are an essential prerequisite for their application in vivo or even in cellulo. The oligoanionic backbone structure of olig...
Autores principales: | Meng, Melissa, Ducho, Christian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009206/ https://www.ncbi.nlm.nih.gov/pubmed/29977397 http://dx.doi.org/10.3762/bjoc.14.111 |
Ejemplares similares
-
Oligonucleotides with Cationic Backbone and Their Hybridization with DNA: Interplay of Base Pairing and Electrostatic Attraction
por: Schmidtgall, Boris, et al.
Publicado: (2017) -
Enhanced Stability of DNA Oligonucleotides with Partially Zwitterionic Backbone Structures in Biological Media †
por: Meng, Melissa, et al.
Publicado: (2018) -
NAA-modified DNA oligonucleotides with zwitterionic backbones: stereoselective synthesis of A–T phosphoramidite building blocks
por: Schmidtgall, Boris, et al.
Publicado: (2015) -
Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS
por: Kandasamy, Pachamuthu, et al.
Publicado: (2022) -
Cellular Targeting of Oligonucleotides by Conjugation with Small Molecules
por: Hawner, Manuel, et al.
Publicado: (2020)