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Core–shell patterning of synthetic hydrogels via interfacial bioorthogonal chemistry for spatial control of stem cell behavior

A new technique is described for the patterning of cell-guidance cues in synthetic extracellular matrices (ECM) for tissue engineering applications. Using s-tetrazine modified hyaluronic acid (HA), bis-trans-cyclooctene (TCO) crosslinkers and monofunctional TCO conjugates, interfacial bioorthogonal...

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Detalles Bibliográficos
Autores principales: Dicker, K. T., Song, J., Moore, A. C., Zhang, H., Li, Y., Burris, D. L., Jia, X., Fox, J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009435/
https://www.ncbi.nlm.nih.gov/pubmed/30009011
http://dx.doi.org/10.1039/c8sc00495a