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Core–shell patterning of synthetic hydrogels via interfacial bioorthogonal chemistry for spatial control of stem cell behavior
A new technique is described for the patterning of cell-guidance cues in synthetic extracellular matrices (ECM) for tissue engineering applications. Using s-tetrazine modified hyaluronic acid (HA), bis-trans-cyclooctene (TCO) crosslinkers and monofunctional TCO conjugates, interfacial bioorthogonal...
Autores principales: | Dicker, K. T., Song, J., Moore, A. C., Zhang, H., Li, Y., Burris, D. L., Jia, X., Fox, J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009435/ https://www.ncbi.nlm.nih.gov/pubmed/30009011 http://dx.doi.org/10.1039/c8sc00495a |
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