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Enhanced Hepatocarcinogenicity Due to Agonists of Peroxisome Proliferator-Activated Receptors in Senescent Rats: Role of Peroxisome Proliferation, Cell Proliferation, and Apoptosis
Exposure to agonists of peroxisome proliferator-activated receptor alpha (PPARα) causes liver cancer in rodents, with aged animals being more susceptible than their younger counterparts to this effect. Treatment with these chemicals produced a five- to sevenfold higher yield of grossly visible hepat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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TheScientificWorldJOURNAL
2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009486/ https://www.ncbi.nlm.nih.gov/pubmed/12805935 http://dx.doi.org/10.1100/tsw.2002.352 |