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Long noncoding RNA OCC-1 suppresses cell growth through destabilizing HuR protein in colorectal cancer

Overexpressed in colon carcinoma-1 (OCC-1) is one of the earliest annotated long noncoding RNAs (lncRNAs) in colorectal cancer (CRC); however, its function remains largely unknown. Here, we revealed that OCC-1 plays a tumor suppressive role in CRC. OCC-1 knockdown by RNA interference promotes cell g...

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Detalles Bibliográficos
Autores principales: Lan, Yang, Xiao, Xuewei, He, Zhengchi, Luo, Yu, Wu, Chuanfang, Li, Ling, Song, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009600/
https://www.ncbi.nlm.nih.gov/pubmed/29931370
http://dx.doi.org/10.1093/nar/gky214