Base-flipping dynamics from an intrahelical to an extrahelical state exerted by thymine DNA glycosylase during DNA repair process

Thymine DNA glycosylase (TDG) is a DNA repair enzyme that excises a variety of mismatched or damaged nucleotides (nts), e.g. dU, dT, 5fC and 5caC. TDG is shown to play essential roles in maintaining genome integrity and correctly programming epigenetic modifications through DNA demethylation. After...

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Detalles Bibliográficos
Autores principales: Da, Lin-Tai, Yu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009601/
https://www.ncbi.nlm.nih.gov/pubmed/29762710
http://dx.doi.org/10.1093/nar/gky386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009601/
https://www.ncbi.nlm.nih.gov/pubmed/29762710
http://dx.doi.org/10.1093/nar/gky386

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