A general strategy for direct, enzyme-catalyzed conjugation of functional compounds to DNA

The methyltransferase enzymes can be applied to deliver a range of modifications to pre-determined sites on large DNA molecules with exceptional specificity and efficiency. To date, however, a limited number of modifications have been delivered in this way because of the complex chemical synthesis t...

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Detalles Bibliográficos
Autores principales: Deen, Jochem, Wang, Su, Van Snick, Sven, Leen, Volker, Janssen, Kris, Hofkens, Johan, Neely, Robert K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009647/
https://www.ncbi.nlm.nih.gov/pubmed/29546351
http://dx.doi.org/10.1093/nar/gky184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009647/
https://www.ncbi.nlm.nih.gov/pubmed/29546351
http://dx.doi.org/10.1093/nar/gky184

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