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Emerin modulates spatial organization of chromosome territories in cells on softer matrices

Cells perceive and relay external mechanical forces into the nucleus through the nuclear envelope. Here we examined the effect of lowering substrate stiffness as a paradigm to address the impact of altered mechanical forces on nuclear structure-function relationships. RNA sequencing of cells on soft...

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Detalles Bibliográficos
Autores principales: Pradhan, Roopali, Ranade, Devika, Sengupta, Kundan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009696/
https://www.ncbi.nlm.nih.gov/pubmed/29684168
http://dx.doi.org/10.1093/nar/gky288