Cargando…

Semisynthesis of Ribonuclease A using Intein-Mediated Protein Ligation

The introduction of non-natural amino acid residues or modules into proteins provides a new means to explore the basis for conformational stability, folding/unfolding behavior, or biological function. We exploited intein-mediated protein ligation to produce a semisynthetic ribonuclease A. Of the 124...

Descripción completa

Detalles Bibliográficos
Autores principales: Arnold, Ulrich, Hinderaker, Matthew P., Raines, Ronald T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009726/
https://www.ncbi.nlm.nih.gov/pubmed/12806173
http://dx.doi.org/10.1100/tsw.2002.855