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Semisynthesis of Ribonuclease A using Intein-Mediated Protein Ligation
The introduction of non-natural amino acid residues or modules into proteins provides a new means to explore the basis for conformational stability, folding/unfolding behavior, or biological function. We exploited intein-mediated protein ligation to produce a semisynthetic ribonuclease A. Of the 124...
Autores principales: | Arnold, Ulrich, Hinderaker, Matthew P., Raines, Ronald T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
TheScientificWorldJOURNAL
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009726/ https://www.ncbi.nlm.nih.gov/pubmed/12806173 http://dx.doi.org/10.1100/tsw.2002.855 |
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