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siRNA Library Screening Identifies a Druggable Immune-Signature Driving Esophageal Adenocarcinoma Cell Growth

BACKGROUND & AIMS: Effective therapeutic approaches are urgently required to tackle the alarmingly poor survival outcomes in esophageal adenocarcinoma (EAC) patients. EAC originates from within the intestinal-type metaplasia, Barrett’s esophagus, a condition arising on a background of gastroesop...

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Detalles Bibliográficos
Autores principales: Duggan, Shane P., Garry, Catherine, Behan, Fiona M., Phipps, Sinead, Kudo, Hiromi, Kirca, Murat, Zaheer, Abdul, McGarrigle, Sarah, Reynolds, John V., Goldin, Robert, Kalloger, Steve E., Schaeffer, David F., Long, Aideen, Strid, Jessica, Kelleher, Dermot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009761/
https://www.ncbi.nlm.nih.gov/pubmed/29930979
http://dx.doi.org/10.1016/j.jcmgh.2018.01.012