Evaluation of morphine‐like effects of the mixed mu/delta agonist morphine‐6‐O‐sulfate in rats: Drug discrimination and physical dependence

Morphine‐6‐O‐sulfate (M6S) is as a mixed‐action mu/delta (μ/δ) opioid receptor agonist with high potency and analgesic efficacy. These studies used assays of drug discrimination and schedule‐controlled responding to assess abuse‐liability, tolerance, and physical dependence as compared to morphine i...

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Detalles Bibliográficos
Autores principales: Yadlapalli, Jai Shankar K., Bommagani, Shoban Babu, Mahelona, Ryan D., Wan, Anqi, Gannon, Brenda M., Penthala, Narsimha R., Dobretsov, Maxim, Crooks, Peter A., Fantegrossi, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009770/
https://www.ncbi.nlm.nih.gov/pubmed/29930811
http://dx.doi.org/10.1002/prp2.403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009770/
https://www.ncbi.nlm.nih.gov/pubmed/29930811
http://dx.doi.org/10.1002/prp2.403

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