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Evaluation of morphine‐like effects of the mixed mu/delta agonist morphine‐6‐O‐sulfate in rats: Drug discrimination and physical dependence
Morphine‐6‐O‐sulfate (M6S) is as a mixed‐action mu/delta (μ/δ) opioid receptor agonist with high potency and analgesic efficacy. These studies used assays of drug discrimination and schedule‐controlled responding to assess abuse‐liability, tolerance, and physical dependence as compared to morphine i...
Autores principales: | Yadlapalli, Jai Shankar K., Bommagani, Shoban Babu, Mahelona, Ryan D., Wan, Anqi, Gannon, Brenda M., Penthala, Narsimha R., Dobretsov, Maxim, Crooks, Peter A., Fantegrossi, William E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009770/ https://www.ncbi.nlm.nih.gov/pubmed/29930811 http://dx.doi.org/10.1002/prp2.403 |
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