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Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers

BACKGROUND & AIMS: Human enteroids present a novel tool to study human intestinal ion transport physiology and pathophysiology. The present study describes the contributions of Cl(-) and HCO(3)(-) secretion to total cyclic adenosine monophosphate (cAMP)-stimulated electrogenic anion secretion in...

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Detalles Bibliográficos
Autores principales: Yin, Jianyi, Tse, Chung-Ming, Avula, Leela Rani, Singh, Varsha, Foulke-Abel, Jennifer, de Jonge, Hugo R., Donowitz, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009799/
https://www.ncbi.nlm.nih.gov/pubmed/29930980
http://dx.doi.org/10.1016/j.jcmgh.2018.02.002