RosettaES: a sampling strategy enabling automated interpretation of difficult cryo-EM maps

Accurate atomic modeling of macromolecular structures into cryo-electron microscopy (cryo-EM) maps is a major challenge, as the moderate resolution makes accurate placement of atoms difficult. We present Rosetta enumerative sampling (RosettaES), an automated tool that uses a fragment-based sampling...

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Detalles Bibliográficos
Autores principales: Frenz, Brandon, Walls, Alexandra C, Egelman, Edward H, Veesler, David, DiMaio, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009829/
https://www.ncbi.nlm.nih.gov/pubmed/28628127
http://dx.doi.org/10.1038/nmeth.4340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009829/
https://www.ncbi.nlm.nih.gov/pubmed/28628127
http://dx.doi.org/10.1038/nmeth.4340

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