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Tricyclic coumarin sulphonate derivatives with alkaline phosphatase inhibitory effects: in vitro and docking studies

Tissue-nonspecific alkaline phosphatase (TNAP) is an important isozyme of alkaline phosphatases, which plays different pivotal roles within the human body. Most importantly, it is responsible for maintaining the balanced ratio of phosphate and inorganic pyrophosphate, thus regulates the extracellula...

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Detalles Bibliográficos
Autores principales: Iqbal, Jamshed, El-Gamal, Mohammed I., Ejaz, Syeda Abida, Lecka, Joanna, Sévigny, Jean, Oh, Chang-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009858/
https://www.ncbi.nlm.nih.gov/pubmed/29390901
http://dx.doi.org/10.1080/14756366.2018.1428193