Carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani chagasi are inhibited by benzoxaboroles

A series of 6-substituted ureido- and thioureido-benzoxaboroles were investigated as inhibitors of carbonic anhydrases from Trypanosoma cruzi (TcCA), and Leishmania donovani chagasi (LdcCA). Both enzymes were inhibited by benzoxaboroles in the micromolar range. Preferential inhibitory potency agains...

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Detalles Bibliográficos
Autores principales: Nocentini, Alessio, Cadoni, Roberta, Dumy, Pascal, Supuran, Claudiu T., Winum, Jean-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009872/
https://www.ncbi.nlm.nih.gov/pubmed/29278948
http://dx.doi.org/10.1080/14756366.2017.1414808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009872/
https://www.ncbi.nlm.nih.gov/pubmed/29278948
http://dx.doi.org/10.1080/14756366.2017.1414808

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