Structure–activity relationships of fraxamoside as an unusual xanthine oxidase inhibitor

Fraxamoside, a macrocyclic secoiridoid glucoside featuring a hydroxytyrosol group, was recently identified as a xanthine oxidase inhibitor (XOI) comparable in potency in vitro to the standard antigout drug allopurinol. However, this activity and its considerably higher value than its derivatives ole...

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Detalles Bibliográficos
Autores principales: Vitale, Rosa Maria, Antenucci, Lina, Gavagnin, Margherita, Raimo, Gennaro, Amodeo, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009875/
https://www.ncbi.nlm.nih.gov/pubmed/28097900
http://dx.doi.org/10.1080/14756366.2016.1252758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009875/
https://www.ncbi.nlm.nih.gov/pubmed/28097900
http://dx.doi.org/10.1080/14756366.2016.1252758

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