Kinetic and structural studies on the interactions of Torpedo californica acetylcholinesterase with two donepezil-like rigid analogues

Acetylcholinesterase inhibitors were introduced for the symptomatic treatment of Alzheimer’s disease (AD). Among the currently approved inhibitors, donepezil (DNP) is one of the most preferred choices in AD therapy. The X-ray crystal structures of Torpedo californica AChE in complex with two novel r...

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Detalles Bibliográficos
Autores principales: Caliandro, Rosanna, Pesaresi, Alessandro, Cariati, Luca, Procopio, Antonio, Oliverio, Manuela, Lamba, Doriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009889/
https://www.ncbi.nlm.nih.gov/pubmed/29651884
http://dx.doi.org/10.1080/14756366.2018.1458030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009889/
https://www.ncbi.nlm.nih.gov/pubmed/29651884
http://dx.doi.org/10.1080/14756366.2018.1458030

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