Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to β sheet in tau protein linked to Alzheimer’s disease

Alzheimer’s disease is a common tauopathy where fibril formation and aggregates are the hallmark of the disease. Efforts targeting amyloid-β plaques have succeeded to remove plaques but failed in clinical trials to improve cognition; thus, the current therapeutic strategy is at preventing tau aggreg...

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Detalles Bibliográficos
Autores principales: Cornejo, Alberto, Aguilar Sandoval, Felipe, Caballero, Leonardo, Machuca, Luis, Muñoz, Patricio, Caballero, Julio, Perry, George, Ardiles, Alejandro, Areche, Carlos, Melo, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009890/
https://www.ncbi.nlm.nih.gov/pubmed/28701064
http://dx.doi.org/10.1080/14756366.2017.1347783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009890/
https://www.ncbi.nlm.nih.gov/pubmed/28701064
http://dx.doi.org/10.1080/14756366.2017.1347783

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