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Novel series of 1,2,4-trioxane derivatives as antimalarial agents

Among three series of 1,2,4-trioxane derivatives, five compounds showed good in vitro antimalarial activity, three compounds of which exhibited better activity against P. falciparum resistant (RKL9) strain than the sensitive (3D7) one. Two best compounds were one from aryl series and the other from...

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Detalles Bibliográficos
Autores principales: Rudrapal, Mithun, Chetia, Dipak, Singh, Vineeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009891/
https://www.ncbi.nlm.nih.gov/pubmed/28870093
http://dx.doi.org/10.1080/14756366.2017.1363742