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Synthesis, biological activity and molecular modelling studies of shikimic acid derivatives as inhibitors of the shikimate dehydrogenase enzyme of Escherichia coli

Shikimic acid (SA) pathway is the common route used by bacteria, plants, fungi, algae, and certain Apicomplexa parasites for the biosynthesis of aromatic amino acids and other secondary metabolites. As this essential pathway is absent in mammals designing inhibitors against implied enzymes may lead...

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Detalles Bibliográficos
Autores principales: Díaz-Quiroz, Dulce Catalina, Cardona-Félix, César Salvador, Viveros-Ceballos, José Luis, Reyes-González, Miguel Angel, Bolívar, Franciso, Ordoñez, Mario, Escalante, Adelfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009893/
https://www.ncbi.nlm.nih.gov/pubmed/29363372
http://dx.doi.org/10.1080/14756366.2017.1422125