Screening assay for inhibitors of a recombinant Streptococcus pneumoniae UDP-glucose pyrophosphorylase

The UDP-glucose pyrophosphorylase of Streptococcus pneumoniae (GalU(Spn)) is absolutely required for the biosynthesis of capsular polysaccharide, the sine qua non virulence factor of pneumococcus. Since the eukaryotic enzymes are completely unrelated to their prokaryotic counterparts, we propose tha...

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Detalles Bibliográficos
Autores principales: Zavala, Agustín, Kovacec, Verónica, Levín, Gustavo, Moglioni, Albertina, Miranda, María Victoria, García, Ernesto, Bonofiglio, Laura, Mollerach, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009895/
https://www.ncbi.nlm.nih.gov/pubmed/28114831
http://dx.doi.org/10.1080/14756366.2016.1247055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009895/
https://www.ncbi.nlm.nih.gov/pubmed/28114831
http://dx.doi.org/10.1080/14756366.2016.1247055

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