Design, synthesis and evaluation of novel cinnamic acid derivatives bearing N-benzyl pyridinium moiety as multifunctional cholinesterase inhibitors for Alzheimer’s disease

A novel family of cinnamic acid derivatives has been developed to be multifunctional cholinesterase inhibitors against AD by fusing N-benzyl pyridinium moiety and different substituted cinnamic acids. In vitro studies showed that most compounds were endowed with a noteworthy ability to inhibit choli...

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Detalles Bibliográficos
Autores principales: Lan, Jin-Shuai, Hou, Jian-Wei, Liu, Yun, Ding, Yue, Zhang, Yong, Li, Ling, Zhang, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009898/
https://www.ncbi.nlm.nih.gov/pubmed/28585866
http://dx.doi.org/10.1080/14756366.2016.1256883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009898/
https://www.ncbi.nlm.nih.gov/pubmed/28585866
http://dx.doi.org/10.1080/14756366.2016.1256883

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