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Systemic alkalinisation delays prostate cancer cell progression in TRAMP mice

The microenvironment of solid tumours is extremely acidic and this condition arises since the precancerous stage. This acidic milieu could therefore provide a useful target for both prophylactic and therapeutic approaches. In TRAMP transgenic mice, an in vivo model of prostate adenocarcinoma (AC), o...

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Detalles Bibliográficos
Autores principales: Astigiano, Simonetta, Puglisi, Andrea, Mastracci, Luca, Fais, Stefano, Barbieri, Ottavia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009900/
https://www.ncbi.nlm.nih.gov/pubmed/28095711
http://dx.doi.org/10.1080/14756366.2016.1252760